Secretor status and ankylosing spondylitis.

Pal, A; Hill, M; Wordsworth, P; Brown, M · J Rheumatol · 1998

case_control · Level III

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Abstract

To assess the genetic association between secretor status and ankylosing spondylitis (AS). A restriction digest method for determining secretor status was developed; 166 patients with AS and 216 healthy British white controls were typed for secretor status using this method. The frequency of nonsecretors among patients with AS (47/166, 28%) was not significantly different from controls (72/216, 33%). Secretor status does not influence susceptibility to AS.

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