Indocyanine green videoangiography of occult choroidal neovascularization: a comparison of scanning laser ophthalmoscope with high-resolution digital fundus camera.

Abstract

To compare the indocyanine green (ICG) angiographic findings of occult choroidal neovascularization (O-CNV) taken by scanning laser ophthalmoscope and high-resolution digital fundus camera. We examined 100 eyes of 100 consecutive patients with ICG angiographic evidence of CNV secondary to age-related macular degeneration. All patients were diagnosed with O-CNV based on fluorescein angiography. Indocyanine green videoangiography was carried out using the scanning laser ophthalmoscope and high-resolution digital fundus camera at the same session. Indocyanine green videoangiography revealed well-defined vessel structure of the O-CNV in 28% of eyes examined by scanning laser ophthalmoscope and in 8% of eyes examined by digital fundus camera. Well-defined focal spots were demonstrated in 37% of eyes examined by scanning laser ophthalmoscope and in 52% of eyes examined by digital fundus camera. Plaques (well-defined) were found in 13% and 35% of eyes examined by scanning laser ophthalmoscope and digital fundus camera, respectively. Indocyanine green videoangiography with scanning laser ophthalmoscopy seems to be superior to the digital fundus camera in delineation of the vessel architecture of O-CNV. Focal spots and plaques are best detected by digital fundus camera.