Stiff-leg syndrome: a focal form of stiff-man syndrome.
case_report · Level V
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- Record sourced from PubMed, PMID 9506561.
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Abstract
We report on 2 patients who presented stiffness and spasms similar to those of stiff-man syndrome (SMS) that were limited to one leg for up to 11 years. Patients had serum glutamic acid decarboxylase (GAD) autoantibodies in high titer, clinical evidence of organ-specific autoimmunity, and electromyographic pattern of continuous motor unit activity with abnormally enhanced exteroceptive reflexes. The clinical and immunological profile suggests that this disorder may be a focal form of SMS.
Medical subject headings
- Leg
- Stiff-Person Syndrome