Polydactyly and psychosis. Five cases of co-occurrence.
case_report · Level V
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- Record sourced from PubMed, PMID 9519074.
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Abstract
Abnormalities presumed to occur during foetal life have been associated with schizophrenia. Polydactyly is a developmental abnormality but no previous association has been reported between polydactyly and functional psychotic illness. Individuals with both polydactyly and a functional psychosis were ascertained during a study of familial schizophrenia. Five such individuals were ascertained in the course of assessing 234 individuals with familial psychosis, giving a rate of polydactyly in the sample of around 10 times the general population rate. This study provides preliminary evidence that polydactyly is over-represented in individuals with familial schizophrenia and related psychotic illnesses.
Medical subject headings
- Polydactyly
- Psychotic Disorders