Cerebellar degeneration following neuroleptic malignant syndrome.
case_report · Level V
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- Record sourced from PubMed, PMID 9519191.
- Also identified by PMC identifier 2431565.
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Abstract
A 55-year-old woman with a history of bipolar affective disorder developed hyperpyrexia, rigidity and depressed consciousness (neuroleptic malignant syndrome) after commencing neuroleptic therapy. On regaining consciousness, she was mute and had signs suggesting pancerebellar involvement. Hyperpyrexia, which is a cardinal feature of neuroleptic malignant syndrome, may have caused cerebellar damage. Neuroleptic malignant syndrome needs both early recognition and prompt treatment to obviate devastating complications.
Medical subject headings
- Cerebellar Diseases
- Mutism
- Neuroleptic Malignant Syndrome