Piperacillin/tazobactam therapy for diabetic foot infection.
case_series · Level IV
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- Record sourced from PubMed, PMID 9542990.
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Abstract
In this study, 29 patients were hospitalized with a diabetic foot infection and were treated with piperacillin/tazobactam. Of these 23 patients who were evaluated for efficacy of treatment, 22 patients improved or were clinically cured. In seven patients (30%), there was persistence of one of the baseline pathogens. Adverse events were reported in 15 patients (58%), three of which were serious. Piperacillin/tazobactam may be useful as monotherapy in diabetic foot infection giving an adequate clinical response and the level of side effects equivalent to those of other broad-spectrum antibiotics.
Medical subject headings
- Diabetic Foot
- Enzyme Inhibitors
- Penicillanic Acid
- Penicillins
- Piperacillin
- Staphylococcal Infections
Anatomy
- foot