Decreased growth hormone response to glucagon in infants after an apnea of infancy.

Chanoine, J P; Rebuffat, E; Kahn, A; Van Vliet, G · J Pediatr · 1998

case_control · Level III

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Abstract

We studied glucagon-induced growth hormone secretion in 9 patients with apnea of infancy and in 55 siblings of children who had died of sudden infant death syndrome, who were included as a comparison group. We observed a 33% decrease in growth hormone secretion in patients with apnea of infancy. However, linear growth remained normal. This finding could be related to either repeated episodes of hypoxia or to abnormal maturation of the autonomous nervous system.

Medical subject headings