Successful treatment of a staphylococcal endocarditis vegetation with tissue plasminogen activator.

Fleming, R E; Barenkamp, S J; Jureidini, S B · J Pediatr · 1998

case_report · Level V

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Abstract

A 930 gm premature infant had Staphylococcal endocarditis with a tricuspid valvular vegetation that was unresponsive to antibiotics and not amenable to resection. Infusion of tissue plasminogen activator over a 3-day period completely lysed the vegetation. The infection cleared with continued antibiotics, and the infant recovered without sequelae.

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