Urinary N-acetyl-beta-N-glucosaminidase in patients with urinary tract infection.

Rodriguez-Cuartero, A; Lopez-Fernandez, A; Pérez-Blanco, F · Eur Urol · 1998

cross_sectional · Level IV

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Abstract

N-acetyl-beta-glucosaminidase (NAG, EC 3.2.1.30) is a lysosomal enzyme present in the proximal convoluted tubule. Increased urinary excretion of NAG has been shown in urinary tract infections. Our results have confirmed that urinary excretion of NAG is significantly higher (33.70 +/- 8.75 U/g Cr) in patients with upper urinary tract infection than in patients with lower urinary tract infection (14.10 +/- 6.80 U/g Cr) and healthy adults.

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