Highly resolved chemical imaging of living cells by using synchrotron infrared microspectrometry.
basic_science · Level V
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- Record sourced from PubMed, PMID 9560189.
- Also identified by PMC identifier 20174.
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Abstract
Using synchrotron radiation as an ultra-bright infrared source, we have been able to map the distributions of functional groups such as proteins, lipids, and nucleic acids inside a single living cell with a spatial resolution of a few microns. In particular, we have mapped the changes in the lipid and protein distributions in both the final stages of cell division and also during necrosis.
Medical subject headings
- Cell Death
- Cell Division
- Spectrophotometry, Infrared