Advances in melanoma therapy.

Johnson, T M; Yahanda, A M; Chang, A E; Fader, D J; Sondak, V K · J Am Acad Dermatol · 1998

review · Level V

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Abstract

This review discusses several advances in melanoma therapy that have recently occurred or are presently in a developmental stage. We discuss the history and present dogma regarding assessment of the regional lymph nodes and adjuvant therapy for melanoma. Of special interest is radiolymphatic sentinel node mapping of the lymph nodes and adjuvant interferon alfa-2b for thick primary lesions and stage III disease. We also discuss several evolving novel and innovative genetic immunotherapy approaches for patients with stage IV disease.

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