Severe neuropathy after high dose carboplatin in three patients receiving multidrug chemotherapy.
case_report · Level V
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- Record sourced from PubMed, PMID 9598687.
- Also identified by PMC identifier 2170092.
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Abstract
Three patients are described who developed a severe neuropathy after chemotherapy with high dose cis-diamine-(1,1-cyclobutane dicarboxylato) platinum (carboplatin). This toxic side effect, which is unusual at conventional doses, might become more frequent as increasing doses are administered to overcome drug resistance in cancer treatment, and might limit its use at very high doses before haematopoietic stem cell transplantation.
Medical subject headings
- Antineoplastic Combined Chemotherapy Protocols
- Carboplatin
- Nervous System Diseases