Infection after transurethral resection of the prostate: variation among centers and correlation with a long-lasting surgical procedure. Association pour la Recherche en Anesthésie-Réanimation.

Abstract

The purpose of this study was to analyze the risk factors of postoperative infection following transurethral resection of the prostate (TURP). 857 consecutive patients scheduled for TURP were included in a French multicenter prospective study (12 surgical centers). For each patient, data were collected and analyzed as risk factors of postoperative infection. Statistical analysis used the chi 2 test or Student's test for univariate analysis, then stepwise logistic regression for multivariate analysis. The incidence of post-TURP infection was 21.6%: urinary tract infection (19.3%) and bacteremia and/or septic shock (2.3%). Multivariate analysis documented three independent risk factors of postoperative infection: preoperative bacteriuria (p < 0.003), duration of surgical procedure > 70 min (p < 0.01) and the surgical center (p < 0.00001). The duration of the surgical procedure is an important postoperative risk factor of infection and there is a major difference between centers in terms of postoperative risk of infection. Further studies are needed to explain this last phenomenon.