T-cell malignant lymphoma with conjunctival involvement.
case_report · Level V
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- Record sourced from PubMed, PMID 9625564.
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Abstract
To report a rare case of T-cell malignant lymphoma involving the conjunctiva. A 63-year-old woman had rapid onset of bilateral perilimbal congestion and chemosis. Perilimbal thickening with corneal infiltration developed 20 days later. Computed tomography incidentally disclosed a right maxillary sinus mass. Biopsy specimens from the maxillary sinus mass and the left limbus were subjected to histopathologic examination and immunohistochemical study. T-cell malignant lymphoma of diffuse large cell type, stage IV, was diagnosed. The patient was treated with combination chemotherapy plus 13-cis-retinoic acid and remained in remission 1 1/2 years after diagnosis. Conjunctival involvement with T-cell lymphoma may present as episcleritis and chemosis.
Medical subject headings
- Antineoplastic Combined Chemotherapy Protocols
- Antineoplastic Combined Chemotherapy Protocols/therapeutic use
- Conjunctival Neoplasms
- Conjunctival Neoplasms/chemistry
- Conjunctival Neoplasms/drug therapy
- Conjunctival Neoplasms/pathology
- Female
- Humans
- Immunohistochemistry
- Immunophenotyping
- Isotretinoin
- Isotretinoin/therapeutic use
- Leukocyte Common Antigens
- Leukocyte Common Antigens/analysis
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Large B-Cell, Diffuse/chemistry
- Lymphoma, Large B-Cell, Diffuse/drug therapy
- Lymphoma, Large B-Cell, Diffuse/pathology
- Lymphoma, T-Cell
- Lymphoma, T-Cell/chemistry
- Lymphoma, T-Cell/drug therapy
- Lymphoma, T-Cell/pathology
- Maxillary Sinus Neoplasms
- Maxillary Sinus Neoplasms/chemistry
- Maxillary Sinus Neoplasms/drug therapy
- Maxillary Sinus Neoplasms/pathology
- Middle Aged
- Neoplasm Staging
- Tomography, X-Ray Computed