Combined liver-kidney transplantation in methylmalonic acidemia.

van 't Hoff, W G; Dixon, M; Taylor, J; Mistry, P; Rolles, K; Rees, L; Leonard, J V · J Pediatr · 1998

case_report · Level V

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Abstract

A 13-year-old boy with non-B12-responsive methylmalonic acidemia (MMA) had chronic renal failure. Hemodialysis led to symptomatic and biochemical improvement. He subsequently received a combined liver-kidney transplant. After 16 months of follow-up he has a normal lifestyle and a marked reduction in plasma and urine methylmalonate.

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