Antibody-negative chronic hepatitis C virus infection in immunocompetent children.
case_report · Level V
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Abstract
Antibody-negative hepatitis C virus (HCV) infection, defined by the presence of HCV viremia in the absence of a serologic response to HCV, was detected in two immunocompetent and symptom-free children; each had a history of exposure to blood products. HCV infection may occasionally explain cryptogenic elevation of aminotransferases, even in the absence of serum anti-HCV. HCV-RNA should be investigated in these cases, particularly in the presence of previous exposure to blood products.
Medical subject headings
- Hepacivirus
- Hepatitis C Antibodies
- Hepatitis C, Chronic