Near fatal anticholinergic intoxication after routine fundoscopy.
case_report · Level V
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- Record sourced from PubMed, PMID 9722045.
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Abstract
We describe a case of severe anticholinergic intoxication following the topical instillation of tropicamide-containing eyedrops. Tropicamide is a short-acting atropine-like derivative and has been regarded as an effective and safe mydriatic. Half an hour after routine fundoscopy, a 62-year-old man experienced two generalized seizures with respiratory arrest and required intubation and mechanical ventilation. The patient was treated with physostigmine and made a full recovery.
Medical subject headings
- Muscarinic Antagonists
- Mydriatics
- Ophthalmoscopy
- Respiratory Insufficiency
- Seizures
- Tropicamide