Upbeat nystagmus: clinicoanatomical correlation.

Janssen, J C; Larner, A J; Morris, H; Bronstein, A M; Farmer, S F · J Neurol Neurosurg Psychiatry · 1998

case_report · Level V

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Abstract

A patient is reported on with isolated upbeating nystagmus with a linear slow phase in whom a solitary lesion, probably inflammatory, was detected radiologically in the dorsal paramedian caudal medulla, encompassing the most caudal of the perihypoglossal nuclei, the nucleus intercalatus of Staderini. The conjunction of a vestibular pattern of nystagmus with this focal lesion runs contrary to a previous suggestion that the nucleus intercalatus may act as a neural integrator for vertical conjugate eye movements.

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