Malignancy in pigmented villonodular synovitis.
case_report · Level V
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- Record sourced from PubMed, PMID 9730332.
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Abstract
Malignant pigmented villonodular synovitis is an extremely rare and controversial disease. We describe malignant change in pigmented villonodular synovitis of the ankle in a patient with an unusually long clinical history. Symptoms began at age 21, metastatic disease developed at age 85, and the patient died 1 year later. The histologic appearance of the malignant tumor differed from that in most reported cases, in that spindle-shaped cells predominated. Lymph node metastasis also developed, a feature uncommon to soft tissue sarcomas.
Medical subject headings
- Ankle Joint
- Bone Neoplasms
- Cell Transformation, Neoplastic
- Synovitis, Pigmented Villonodular
- Tibia
Anatomy
- ankle
- tibia