Ibuprofen-induced hepatotoxicity in patients with chronic hepatitis C: a case series.

Riley, T R; Smith, J P · Am J Gastroenterol · 1998

case_series · Level V

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Abstract

Hepatitis C is a common chronic infection. Nonsteroidal anti-inflammatory drugs are commonly ingested both over-the-counter and by prescription. This case report describes three cases where ibuprofen use leads to a marked rise in hepatic transaminases with one case repeating on rechallenge. These cases support the recommendation of acetaminophen over nonsteroidal antiinflammatory drug use in patients with chronic hepatitis C.

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