Neuroprotection for Parkinson's disease.
review · Level V
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- Record sourced from PubMed, PMID 9749588.
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Abstract
Levodopa is the most effective drug available for the treatment of Parkinson's disease (PD). As a precursor of dopamine, levodopa causes an increase in brain dopamine, which is depleted in PD. However, long-term levodopa therapy is associated with complications such as dyskinesias, motor fluctuations, and mental status changes. The treatment of these side effects is a major challenge for the clinician.
Medical subject headings
- Antiparkinson Agents
- Dopamine Agents
- Levodopa
- Neuroprotective Agents
- Parkinson Disease