Autoimmune progesterone dermatitis: treatment with oophorectomy.
case_report · Level V
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- Record sourced from PubMed, PMID 9767301.
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Abstract
Autoimmune progesterone dermatitis is a rare manifestation of hypersensitivity to endogenous hormones with polymorphic clinical manifestations. We report a 28-year-old woman with a 5-year history of mucocutaneous erythema multiforme occurring cyclically in the premenstrual period. Progesterone sensitivity was demonstrated by challenge test with medroxyprogesterone acetate. Treatments with oestrogens, tamoxifen and triptorelin had to be withdrawn because of intolerable adverse effects. Oophorectomy finally cured the disease.
Medical subject headings
- Autoimmune Diseases
- Erythema Multiforme
- Ovariectomy
- Progesterone