Cushing's disease treated by trans-sphenoidal selective adenomectomy in mid-pregnancy.
case_report · Level V
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- Record sourced from PubMed, PMID 9771323.
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Abstract
The clinical course and diagnosis of a patient with Cushing's disease complicated by pregnancy is described, and the anaesthetic management of trans-sphenoidal selective adenomectomy performed during the second trimester outlined. Problems included obesity, diabetes, hypertension and a suboptimal airway. Fibreoptic awake intubation and intravenous anaesthesia were used. Insulin requirements decreased substantially after surgery. Early administration of hydrocortisone after surgery avoided the risk of an addisonian crisis but delayed biochemical confirmation of a metabolic cure.
Medical subject headings
- Anesthesia, General
- Cushing Syndrome
- Pregnancy Complications