The pathogenesis of psoriasis and the mechanism of action of tazarotene.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 9777790.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The 3 major features of psoriasis--abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin--can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of these markers. Tazarotene helps to normalize the levels of the markers, thereby bringing about clinical improvement.
Medical subject headings
- Keratolytic Agents
- Nicotinic Acids
- Psoriasis