Lamotrigine-associated anticonvulsant hypersensitivity syndrome.
case_series · Level IV
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- Record sourced from PubMed, PMID 9781550.
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Abstract
We systematically reviewed and analyzed published and unpublished cases of lamotrigine-associated adverse drug reactions consistent with the features of the anticonvulsant hypersensitivity syndrome (AHS) to identify characteristics of the syndrome. We identified 26 cases (mean age, 28+/-18 years; range, 3.5 to 74 years; 54% female), of which nine were published. The characteristics of the syndrome associated with lamotrigine are comparable to AHS induced by older aromatic anticonvulsants.
Medical subject headings
- Anticonvulsants
- Drug Hypersensitivity
- Epilepsy
- Triazines