Devic's neuromyelitis optica: a prospective study of seven patients treated with prednisone and azathioprine.
prospective_cohort · Level II
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Abstract
Seven newly diagnosed patients with Devic's neuromyelitis optica were treated with long-term prednisone and azathioprine, and were followed every 2 months for at least 18 months. Their Expanded Disability Status Scale score improved significantly (mean at baseline, 9; mean at 18 months, 3; p < 0.005), and no relapses occurred for more than 18 months. Multicenter controlled studies are needed to prove the efficacy of this therapeutic regimen.
Medical subject headings
- Anti-Inflammatory Agents
- Azathioprine
- Immunosuppressive Agents
- Neuromyelitis Optica
- Prednisone