Brugada syndrome associated with an autonomic disorder.
case_report · Level V
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- Record sourced from PubMed, PMID 9813569.
- Also identified by PMC identifier 1728791.
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Abstract
A 44 year old man with Brugada syndrome and ventricular fibrillation had an autonomic disorder, shown by spectral analysis of heart rate variability and 123I-MIBG myocardial scintigraphy. Periodic variation of the ST segments was detected by Holter ECG. Increased high frequency power (0.15-0.40 Hz), an index of parasympathetic nerve activity, was observed just before ST segment elevation. In addition, local dysfunction of sympathetic nerves in the left ventricle was detected by 123I-MIBG myocardial scintigraphy. Unbalanced autonomic nerve function plays an important role in inducing Brugada-type ECG signs.
Medical subject headings
- Autonomic Nervous System
- Autonomic Nervous System Diseases
- Bundle-Branch Block
- Ventricular Fibrillation