Idiopathic progressive hyalinizing and calcifying CNS vasculopathy.

Moussouttas, M; Morgello, S; Geraci, A; Chan, B; Wallace, S · Neurology · 1998

case_report · Level V

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Abstract

We present a female adolescent with intermittently progressive neurologic deficits over a period of 7 years. Serial imaging studies showed a calcifying lesion with increasing enhancement, signal abnormalities from the subcortex to the medulla, and hemispheric volume loss. Stereotactic biopsies disclosed a hyalinizing and calcifying vasculopathy involving the penetrating vessels. The vasculopathy may result in ischemic lesions responsible for the severe deficits.

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