Amygdala atrophy and seizure outcome after temporal lobe epilepsy surgery.
retrospective_cohort · Level III
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Abstract
Surgical outcome in hippocampal atrophy (n = 44) and amygdalohippocampal atrophy (n = 14) were compared. Hippocampal atrophy had better seizure-free outcome than amygdalohippocampal atrophy (80% versus 50%, p = 0.043). Severity of hippocampal atrophy correlated with duration of epilepsy in patients with hippocampal atrophy (r = 0.4, p = 0.007), but not in those with amygdalohippocampal atrophy, suggesting that these two groups may have a different pathogenesis.
Medical subject headings
- Amygdala
- Epilepsy, Temporal Lobe
- Hippocampus
- Seizures