Fatal enterovirus 71 encephalomyelitis.

Lum, L C; Wong, K T; Lam, S K; Chua, K B; Goh, A Y; Lim, W L; Ong, B B; Paul, G et al. · J Pediatr · 1998

case_report · Level V

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Abstract

During an outbreak of hand-foot-mouth disease caused by enterovirus 71 (EV-71) in 1997, 4 children presented with sudden cardiopulmonary collapse and minimal neurologic features. All children received cardiopulmonary resuscitation but died within a few hours of admission. Postmortem studies showed infection by EV-71 with extensive damage to the medulla and pons. We postulate an etiologic link between EV-71 and brainstem encephalomyelitis as the cause of pulmonary edema and death.

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