Zinc fingers in Caenorhabditis elegans: finding families and probing pathways.
review · Level V
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Abstract
More than 3 percent of the protein sequences inferred from the Caenorhabditis elegans genome contain sequence motifs characteristic of zinc-binding structural domains, and of these more than half are believed to be sequence-specific DNA-binding proteins. The distribution of these zinc-binding domains among the genomes of various organisms offers insights into the role of zinc-binding proteins in evolution. In addition, the complete genome sequence of C. elegans provides an opportunity to analyze, and perhaps predict, pathways of transcriptional regulation.
Medical subject headings
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Helminth Proteins
- Zinc Fingers