Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures.

Mirza, W U; Rak, I W; Thadani, V M; Cereghino, J J; Garnett, W R; Brown, L M; Zhang, Y; Belendiuk, G W · Neurology · 1998

case_series · Level IV

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Abstract

We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with complex partial seizures. Ninety-one percent of the patients successfully completed the 6-month trial with good seizure control, with a significant improvement in quality of life. We conclude that switching patients with complex partial seizures from multiple daily-dose carbamazepine to twice-daily Carbatrol on a milligram-to-milligram basis is relatively safe.

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