Pulse cyclophosphamide therapy in chronic inflammatory demyelinating polyneuropathy.
case_series · Level IV
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- Record sourced from PubMed, PMID 9855536.
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Abstract
Fifteen patients with chronic inflammatory demyelinating neuropathy (CIDP) were treated with pulse intravenous cyclophosphamide (IVCY) monthly for up to 6 months. Eleven patients reached a complete remission; only one patient worsened. Complications included nausea, vomiting, anemia, and hair loss. This case series suggests that monthly IVCY is beneficial in the treatment of CIDP and warrants a controlled study.
Medical subject headings
- Cyclophosphamide
- Demyelinating Diseases
- Immunosuppressive Agents
- Polyneuropathies