Hereditary spastic paraplegia with a thin corpus callosum and thalamic involvement in Japan.

Ueda, M; Katayama, Y; Kamiya, T; Mishina, M; Igarashi, H; Okubo, S; Senda, M; Iwabuchi, K et al. · Neurology · 1998

case_report · Level V

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Abstract

The authors examined two Japanese siblings with a recessive hereditary spastic paraplegia (HSP) with dementia and a thin corpus callosum. Both showed thalamic glucose hypometabolism on PET. Recessive HSP with a thin corpus callosum is a rare disorder, with less than 20 reported patients, that may be a Japanese subtype of HSP.

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