Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease.
case_series · Level IV
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- Record sourced from PubMed, PMID 9855542.
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Abstract
We evaluated motor function in 41 consecutive PD patients undergoing unilateral MRI/microelectrode-guided posteroventral pallidotomy to determine whether the motor effects of levodopa therapy change after surgery. Total Unified Parkinson's Disease Rating Scale motor "off" and motor "on" subscores all improved and the rapidity of action, magnitude, and duration of motor response to levodopa therapy were all maintained after pallidotomy.
Medical subject headings
- Antiparkinson Agents
- Globus Pallidus
- Levodopa
- Motor Activity
- Parkinson Disease