Early onset of nephrotic syndrome after treatment with D-penicillamine in a patient with Wilson's disease.

Siafakas, C G; Jonas, M M; Alexander, S; Herrin, J; Furuta, G T · Am J Gastroenterol · 1998

case_report · Level V

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Abstract

Wilson's disease responds to a variety of treatments including D-penicillamine and trientene. Nephrotic syndrome is a late complication of D-penicillamine treatment. We report a pediatric patient with Wilson's disease who developed nephrotic syndrome 2 wk after beginning D-penicillamine. His nephrosis resolved and his disease is quiescent with trientene treatment.

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