Sclerodermatous graft-versus-host disease after donor leucocyte infusion.
case_report · Level V
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- Record sourced from PubMed, PMID 9892961.
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Abstract
Leucocyte infusion from the marrow donor is a new therapeutic option to avoid repeated bone marrow transplants in patients with recurrent leukaemia. The treatment is based on the fact that alloreactive donor immune cells may recognize and eliminate residual leukaemia cells. This phenomenon has been called graft-versus-leukaemia. We describe a patient who received donor leucocyte infusion for a relapsed chronic myeloid leukaemia after his second bone marrow transplant and developed sclerodermatous graft-versus-host disease.
Medical subject headings
- Graft vs Host Disease
- Leukocyte Transfusion
- Scleroderma, Systemic