Glyoxalase I activity in human prostate cancer: a potential marker and importance in chemotherapy.
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Abstract
To provide information on the activity of Gly-I in prostate cancer. We performed qualitative Gly-I assay on prostate tissues. Gly-I activity between prostate cancer and noncancerous specimens differed substantially and significantly, although such activity also varied somewhat among cancer specimens. Gly-I activity is indeed higher in cancerous than in noncancerous specimens, suggesting that it may play a role in prostate cancer homeostasis and survival.
Medical subject headings
- Lactoylglutathione Lyase
- Prostatic Neoplasms