Opioid-induced itching: morphine sulfate and hydromorphone hydrochloride.

Katcher, J; Walsh, D · J Pain Symptom Manage · 1999

case_report · Level V

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Abstract

We describe a case of severe morphine-induced itch unrelieved by antihistamines, which responded to a change to hydromorphone. The possible mechanisms of opioid-induced itch are briefly discussed. It is unclear if it is due to histamine release, an opioid-receptor mediated effect, or idiosyncratic drug reaction.

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