Complications of sickle cell anemia in adults: guidelines for effective management.
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Abstract
Thanks to improved treatment, most patients with sickle cell disease now survive long into adulthood, but they still face a lifetime of complications and crises, including chronic hemolytic anemia, vascular occlusions, pain, and the side effects of therapy. This article consists of guidelines for diagnosing and treating problems encountered in adult patients with sickle cell disease.