JPred: a consensus secondary structure prediction server.

Cuff, J A; Clamp, M E; Siddiqui, A S; Finlay, M; Barton, G J · Bioinformatics · 1998

basic_science · Level V

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Abstract

An interactive protein secondary structure prediction Internet server is presented. The server allows a single sequence or multiple alignment to be submitted, and returns predictions from six secondary structure prediction algorithms that exploit evolutionary information from multiple sequences. A consensus prediction is also returned which improves the average Q3 accuracy of prediction by 1% to 72.9%. The server simplifies the use of current prediction algorithms and allows conservation patterns important to structure and function to be identified. http://barton.ebi.ac.uk/servers/jpred.h tml geoff@ebi.ac.uk

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