Retrograde intra-arterial infusion of prostaglandin E1 and heparin for the no-reflow phenomenon after oromandibular reconstruction with a free fibular flap.
case_report · Level V
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Abstract
The authors encountered a patient with a tumor of the floor of the mouth in whom the no-reflow phenomenon occurred after excision of the lesion and the mandible, followed by reconstruction using a free fibular flap. A catheter was inserted retrogradely from the point where the peroneal artery had been ligated at the time of flap preparation. Continuous intra-arterial infusion of prostaglandin E1 and heparin was performed, and the flap survived. This method salvaged free flaps subject to the no-reflow phenomenon.
Medical subject headings
- Alprostadil
- Anticoagulants
- Fibrinolytic Agents
- Heparin
- Infusions, Intra-Arterial
- Mandibular Neoplasms
- Mouth Neoplasms
- Postoperative Complications
- Surgical Flaps
- Thrombosis